Florence County Sheriff's Office Florence County Sheriff's Office Search | Advanced Search | New Members | Coupons and Discounts | All Categories Government & Education >> Government Officials/Agencies/Individuals Florence County Sheriff's Office 6719 Friendfield RdEffingham, SC 29541 (843) 665-2121 | fax: (843) 673-0348 Visit Site Send a message to: Florence County Sheriff's Office Your Name: Your Email: Subject: Message: (Date: 5/20/2025)