Directions to Florence County Sheriff's Office Directions to Florence County Sheriff's Office Search | Advanced Search | New Members | Coupons and Discounts | All Categories Health Care >> Ambulance Service/Emergency Florence County Sheriff's Office 6719 Friendfield RdEffingham, SC 29541 (843) 665-2121 | fax: (843) 673-0348 Visit Site Get directions to: Florence County Sheriff's Office, 6719 Friendfield Rd, Effingham SC Get directions from: Click to Print This Page